Modelling organophosphate intoxication in C. elegans highlights nicotinic acetylcholine receptor determinants that mitigate poisoning

Organophosphate intoxication via acetylcholinesterase inhibition executes neurotoxicity via hyper stimulation of acetylcholine receptors. Here, we use the organophosphate paraoxon-ethyl to treat C. elegans and use its impact on pharyngeal pumping as a bio-assay to model poisoning through these neuro...

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Detalles Bibliográficos
Autores principales: Izquierdo, Patricia G., Charvet, Claude L., Neveu, Cedric, Green, A. Christopher, Tattersall, John E. H., Holden-Dye, Lindy, O’Connor, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121051/
https://www.ncbi.nlm.nih.gov/pubmed/37083685
http://dx.doi.org/10.1371/journal.pone.0284786

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121051/
https://www.ncbi.nlm.nih.gov/pubmed/37083685
http://dx.doi.org/10.1371/journal.pone.0284786

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