Cargando…

FAK downregulation suppresses stem-like properties and migration of human colorectal cancer cells

Focal adhesion kinase (FAK) is a cytoplasmic protein tyrosine kinase, which is overexpressed in colorectal cancer cells. FAK could be activated by phosphorylation to participate in the transduction of multiple signaling pathways and self-renewal of cancer stem cells. Whether the downregulation of FA...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Chunyan, Zhang, Wenlu, Liu, Chengxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121060/
https://www.ncbi.nlm.nih.gov/pubmed/37083591
http://dx.doi.org/10.1371/journal.pone.0284871