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Increased Network Inhibition in the Dentate Gyrus of Adult Neuroligin-4 Knock-Out Mice

Loss-of-function mutations in neuroligin-4 (Nlgn4), a member of the neuroligin family of postsynaptic adhesion proteins, cause autism spectrum disorder in humans. Nlgn4 knockout (KO) in mice leads to social behavior deficits and complex alterations of synaptic inhibition or excitation, depending on...

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Detalles Bibliográficos
Autores principales: Muellerleile, Julia, Vnencak, Matej, Sethi, Mohammad Valeed Ahmed, Jungenitz, Tassilo, Schwarzacher, Stephan W., Jedlicka, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121080/
https://www.ncbi.nlm.nih.gov/pubmed/37080762
http://dx.doi.org/10.1523/ENEURO.0471-22.2023