ESCRT recruitment to SARS-CoV-2 spike induces virus-like particles that improve mRNA vaccines

Prime-boost regimens for COVID-19 vaccines elicit poor antibody responses against Omicron-based variants and employ frequent boosters to maintain antibody levels. We present a natural infection-mimicking technology that combines features of mRNA- and protein nanoparticle-based vaccines through encod...

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Detalles Bibliográficos
Autores principales: Hoffmann, Magnus A.G., Yang, Zhi, Huey-Tubman, Kathryn E., Cohen, Alexander A., Gnanapragasam, Priyanthi N.P., Nakatomi, Leesa M., Storm, Kaya N., Moon, Woohyun J., Lin, Paulo J.C., West, Anthony P., Bjorkman, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121106/
https://www.ncbi.nlm.nih.gov/pubmed/37146611
http://dx.doi.org/10.1016/j.cell.2023.04.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121106/
https://www.ncbi.nlm.nih.gov/pubmed/37146611
http://dx.doi.org/10.1016/j.cell.2023.04.024

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