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CBP and Gcn5 drive zygotic genome activation independently of their catalytic activity

Zygotic genome activation (ZGA) is a crucial step of embryonic development. So far, little is known about the role of chromatin factors during this process. Here, we used an in vivo RNA interference reverse genetic screen to identify chromatin factors necessary for embryonic development in Drosophil...

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Detalles Bibliográficos
Autores principales: Ciabrelli, Filippo, Rabbani, Leily, Cardamone, Francesco, Zenk, Fides, Löser, Eva, Schächtle, Melanie A., Mazina, Marina, Loubiere, Vincent, Iovino, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121174/
https://www.ncbi.nlm.nih.gov/pubmed/37083536
http://dx.doi.org/10.1126/sciadv.adf2687