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Characterisation of an Escherichia coli line that completely lacks ribonucleotide reduction yields insights into the evolution of parasitism and endosymbiosis

Life requires ribonucleotide reduction for de novo synthesis of deoxyribonucleotides. As ribonucleotide reduction has on occasion been lost in parasites and endosymbionts, which are instead dependent on their host for deoxyribonucleotide synthesis, it should in principle be possible to knock this pr...

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Detalles Bibliográficos
Autores principales: Arras, Samantha DM, Sibaeva, Nellie, Catchpole, Ryan J, Horinouchi, Nobuyuki, Si, Dayong, Rickerby, Alannah M, Deguchi, Kengo, Hibi, Makoto, Tanaka, Koichi, Takeuchi, Michiki, Ogawa, Jun, Poole, Anthony M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121223/
https://www.ncbi.nlm.nih.gov/pubmed/37022136
http://dx.doi.org/10.7554/eLife.83845