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Replication Timing Aberration of KIF14 and MDM4 / PI3KC 2 β Alleles and Aneuploidy as Markers of Chromosomal Instability and Poor Treatment Response in Ewing Family Tumor Patients

Replication timing of allelic gene pairs is strictly regulated according to expression, genome stability, and epigenetic changes, and tumorigenesis may be associated with changes in the allelic replication in various tumors. Our aim was to determine whether such alterations had a prognostic value in...

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Detalles Bibliográficos
Autores principales: Ayala, Fernanda Rocha Rojas, Martin, Jeffrey William, Bertuzzo, Carmen Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121373/
https://www.ncbi.nlm.nih.gov/pubmed/37091312
http://dx.doi.org/10.1055/s-0043-1768238