Cargando…
Replication Timing Aberration of KIF14 and MDM4 / PI3KC 2 β Alleles and Aneuploidy as Markers of Chromosomal Instability and Poor Treatment Response in Ewing Family Tumor Patients
Replication timing of allelic gene pairs is strictly regulated according to expression, genome stability, and epigenetic changes, and tumorigenesis may be associated with changes in the allelic replication in various tumors. Our aim was to determine whether such alterations had a prognostic value in...
Autores principales: | Ayala, Fernanda Rocha Rojas, Martin, Jeffrey William, Bertuzzo, Carmen Silvia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Georg Thieme Verlag KG
2023
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121373/ https://www.ncbi.nlm.nih.gov/pubmed/37091312 http://dx.doi.org/10.1055/s-0043-1768238 |
Ejemplares similares
-
Re-replication of a Centromere Induces Chromosomal Instability and Aneuploidy
por: Hanlon, Stacey L., et al.
Publicado: (2015) -
Chromosomal Instability, Aneuploidy, and Cancer
por: Bakhoum, Samuel F., et al.
Publicado: (2014) -
Loss of Ewing sarcoma EWS allele promotes tumorigenesis by inducing chromosomal instability in zebrafish
por: Park, Hyewon, et al.
Publicado: (2016) -
Aneuploidy and chromosomal instability in cancer: a jackpot to chaos
por: Giam, Maybelline, et al.
Publicado: (2015) -
Chromosome Instability and Mosaic Aneuploidy in Neurodegenerative and Neurodevelopmental Disorders
por: Potter, Huntington, et al.
Publicado: (2019)