VprBP/DCAF1 regulates p53 function and stability through site-specific phosphorylation

VprBP (also known as DCAF1) is a recently identified kinase that is overexpressed in cancer cells and serves as a major determinant for epigenetic gene silencing and tumorigenesis. The role of VprBP in driving target gene inactivation has been largely attributed to its ability to mediate histone H2A...

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Detalles Bibliográficos
Autores principales: Ghate, Nikhil Baban, Kim, Sungmin, Mehmood, Roasa, Shin, Yonghwan, Kim, Kyunghwan, An, Woojin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121470/
https://www.ncbi.nlm.nih.gov/pubmed/37041410
http://dx.doi.org/10.1038/s41388-023-02685-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121470/
https://www.ncbi.nlm.nih.gov/pubmed/37041410
http://dx.doi.org/10.1038/s41388-023-02685-8

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