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The role of tyrosine hydroxylase as a key player in neuromelanin synthesis and the association of neuromelanin with Parkinson’s disease

The dark pigment neuromelanin (NM) is abundant in cell bodies of dopamine (DA) neurons in the substantia nigra (SN) and norepinephrine (NE) neurons in the locus coeruleus (LC) in the human brain. During the progression of Parkinson’s disease (PD), together with the degeneration of the respective cat...

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Detalles Bibliográficos
Autores principales: Nagatsu, Toshiharu, Nakashima, Akira, Watanabe, Hirohisa, Ito, Shosuke, Wakamatsu, Kazumasa, Zucca, Fabio A., Zecca, Luigi, Youdim, Moussa, Wulf, Maximilian, Riederer, Peter, Dijkstra, Johannes M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121510/
https://www.ncbi.nlm.nih.gov/pubmed/36939908
http://dx.doi.org/10.1007/s00702-023-02617-6