Associating broad and clinically defined polygenic scores for depression with depression-related phenotypes

Twin studies indicate that 30–40% of the disease liability for depression can be attributed to genetic differences. Here, we assess the explanatory ability of polygenic scores (PGS) based on broad- (PGS(BD)) and clinical- (PGS(MDD)) depression summary statistics from the UK Biobank in an independent...

Descripción completa

Detalles Bibliográficos
Autores principales: McGeary, John E., Benca-Bachman, Chelsie E., Risner, Victoria A., Beevers, Christopher G., Gibb, Brandon E., Palmer, Rohan H. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121555/
https://www.ncbi.nlm.nih.gov/pubmed/37085695
http://dx.doi.org/10.1038/s41598-023-33645-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121555/
https://www.ncbi.nlm.nih.gov/pubmed/37085695
http://dx.doi.org/10.1038/s41598-023-33645-7

Ejemplares similares