LPS induces microglial activation and GABAergic synaptic deficits in the hippocampus accompanied by prolonged cognitive impairment

Neuroinflammation impacts the brain and cognitive behavior through microglial activation. In this study, we determined the temporal sequence from microglial activation to synaptic dysfunction and cognitive behavior induced by neuroinflammation in mice. We found that LPS injection activated microglia...

Descripción completa

Detalles Bibliográficos
Autores principales: Jung, Hyeji, Lee, Dongsu, You, Heejung, Lee, Myungha, Kim, Hyeonho, Cheong, Eunji, Um, Ji Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121592/
https://www.ncbi.nlm.nih.gov/pubmed/37085584
http://dx.doi.org/10.1038/s41598-023-32798-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121592/
https://www.ncbi.nlm.nih.gov/pubmed/37085584
http://dx.doi.org/10.1038/s41598-023-32798-9

Ejemplares similares