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LPS induces microglial activation and GABAergic synaptic deficits in the hippocampus accompanied by prolonged cognitive impairment
Neuroinflammation impacts the brain and cognitive behavior through microglial activation. In this study, we determined the temporal sequence from microglial activation to synaptic dysfunction and cognitive behavior induced by neuroinflammation in mice. We found that LPS injection activated microglia...
Autores principales: | Jung, Hyeji, Lee, Dongsu, You, Heejung, Lee, Myungha, Kim, Hyeonho, Cheong, Eunji, Um, Ji Won |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121592/ https://www.ncbi.nlm.nih.gov/pubmed/37085584 http://dx.doi.org/10.1038/s41598-023-32798-9 |
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