Machine learning reveals limited contribution of trans-only encoded variants to the HLA-DQ immunopeptidome

Human leukocyte antigen (HLA) class II antigen presentation is key for controlling and triggering T cell immune responses. HLA-DQ molecules, which are believed to play a major role in autoimmune diseases, are heterodimers that can be formed as both cis and trans variants depending on whether the α-...

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Detalles Bibliográficos
Autores principales: Nilsson, Jonas Birkelund, Kaabinejadian, Saghar, Yari, Hooman, Peters, Bjoern, Barra, Carolina, Gragert, Loren, Hildebrand, William, Nielsen, Morten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121683/
https://www.ncbi.nlm.nih.gov/pubmed/37085710
http://dx.doi.org/10.1038/s42003-023-04749-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121683/
https://www.ncbi.nlm.nih.gov/pubmed/37085710
http://dx.doi.org/10.1038/s42003-023-04749-7

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