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Machine learning reveals limited contribution of trans-only encoded variants to the HLA-DQ immunopeptidome
Human leukocyte antigen (HLA) class II antigen presentation is key for controlling and triggering T cell immune responses. HLA-DQ molecules, which are believed to play a major role in autoimmune diseases, are heterodimers that can be formed as both cis and trans variants depending on whether the α-...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121683/ https://www.ncbi.nlm.nih.gov/pubmed/37085710 http://dx.doi.org/10.1038/s42003-023-04749-7 |