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Mobilization of monocytic myeloid-derived suppressor cells is regulated by PTH1R activation in bone marrow stromal cells

Myeloid-derived suppressor cells (MDSCs) are bone marrow (BM)-derived immunosuppressive cells in the tumor microenvironment, but the mechanism of MDSC mobilization from the BM remains unclear. We investigated how BM stromal cell activation by PTH1R contributes to MDSC mobilization. PTH1R activation...

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Detalles Bibliográficos
Autores principales: Lee, Eun Jung, Lee, Kyoung Jin, Jung, Seungpil, Park, Kyong Hwa, Park, Serk In
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121701/
https://www.ncbi.nlm.nih.gov/pubmed/37085481
http://dx.doi.org/10.1038/s41413-023-00255-y