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Metformin Attenuates Tau Pathology in Tau-Seeded PS19 Mice

Accumulation of neurofibrillary tangles (NFTs) composed of hyperphosphorylated tau is a histopathological hallmark of Alzheimer’s disease (AD) and related tauopathies. Growing evidence demonstrated that tau pathology in AD spreads in a prion-like manner. Previous studies showed that metformin might...

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Detalles Bibliográficos
Autores principales: Zhao, Shuai, Fan, Ziqi, Zhang, Xinyi, Li, Zheyu, Shen, Ting, Li, Kaicheng, Yan, Yaping, Yuan, Yunfeng, Pu, Jiali, Tian, Jun, Liu, Zhirong, Chen, Yanxing, Zhang, Baorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121992/
https://www.ncbi.nlm.nih.gov/pubmed/36422837
http://dx.doi.org/10.1007/s13311-022-01316-6