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Metformin Attenuates Tau Pathology in Tau-Seeded PS19 Mice
Accumulation of neurofibrillary tangles (NFTs) composed of hyperphosphorylated tau is a histopathological hallmark of Alzheimer’s disease (AD) and related tauopathies. Growing evidence demonstrated that tau pathology in AD spreads in a prion-like manner. Previous studies showed that metformin might...
Autores principales: | Zhao, Shuai, Fan, Ziqi, Zhang, Xinyi, Li, Zheyu, Shen, Ting, Li, Kaicheng, Yan, Yaping, Yuan, Yunfeng, Pu, Jiali, Tian, Jun, Liu, Zhirong, Chen, Yanxing, Zhang, Baorong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121992/ https://www.ncbi.nlm.nih.gov/pubmed/36422837 http://dx.doi.org/10.1007/s13311-022-01316-6 |
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