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Bicalutamide and Trehalose Ameliorate Spinal and Bulbar Muscular Atrophy Pathology in Mice

Spinal and bulbar muscular atrophy (SBMA) is characterized by motor neuron (MN) degeneration that leads to slowly progressive muscle weakness. It is considered a neuromuscular disease since muscle has a primary role in disease onset and progression. SBMA is caused by a CAG triplet repeat expansion i...

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Detalles Bibliográficos
Autores principales: Galbiati, Mariarita, Meroni, Marco, Boido, Marina, Cescon, Matilde, Rusmini, Paola, Crippa, Valeria, Cristofani, Riccardo, Piccolella, Margherita, Ferrari, Veronica, Tedesco, Barbara, Casarotto, Elena, Chierichetti, Marta, Cozzi, Marta, Mina, Francesco, Cicardi, Maria Elena, Pedretti, Silvia, Mitro, Nico, Caretto, Anna, Risè, Patrizia, Sala, Angelo, Lieberman, Andrew P., Bonaldo, Paolo, Pennuto, Maria, Vercelli, Alessandro, Poletti, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10121997/
https://www.ncbi.nlm.nih.gov/pubmed/36717478
http://dx.doi.org/10.1007/s13311-023-01343-x