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Rhinovirus-induced epithelial RIG-I inflammasome suppresses antiviral immunity and promotes inflammation in asthma and COVID-19

Rhinoviruses and allergens, such as house dust mite are major agents responsible for asthma exacerbations. The influence of pre-existing airway inflammation on the infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is largely unknown. We analyse mechanisms of response to vir...

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Detalles Bibliográficos
Autores principales: Radzikowska, Urszula, Eljaszewicz, Andrzej, Tan, Ge, Stocker, Nino, Heider, Anja, Westermann, Patrick, Steiner, Silvio, Dreher, Anita, Wawrzyniak, Paulina, Rückert, Beate, Rodriguez-Coira, Juan, Zhakparov, Damir, Huang, Mengting, Jakiela, Bogdan, Sanak, Marek, Moniuszko, Marcin, O’Mahony, Liam, Jutel, Marek, Kebadze, Tatiana, Jackson, David J., Edwards, Michael R., Thiel, Volker, Johnston, Sebastian L., Akdis, Cezmi A., Sokolowska, Milena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122208/
https://www.ncbi.nlm.nih.gov/pubmed/37087523
http://dx.doi.org/10.1038/s41467-023-37470-4