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METTL3 facilitates immunosurveillance by inhibiting YTHDF2-mediated NLRC5 mRNA degradation in endometrial cancer

BACKGROUND: N6-methyladenosine (m6A) methylation is the most abundant chemical posttranscriptional modification of mRNA, and it is associated with the regulation of the immune response to tumors. However, the function of m6A modification in the immune response to endometrial cancer (EC) remains unkn...

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Detalles Bibliográficos
Autores principales: Zhan, Lei, Zhang, Jing, Zhang, Jun-Hui, Liu, Xiao-Jing, Guo, Bao, Chen, Jia-Hua, Tang, Zhen-Hai, Wang, Wen-Yan, Wang, Qing-Yuan, Wei, Bing, Cao, Yun-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122371/
https://www.ncbi.nlm.nih.gov/pubmed/37085864
http://dx.doi.org/10.1186/s40364-023-00479-4