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Treatment for ovarian clear cell carcinoma with combined inhibition of WEE1 and ATR

BACKGROUND: Standard platinum-based therapy for ovarian cancer is inefficient against ovarian clear cell carcinoma (OCCC). OCCC is a distinct subtype of epithelial ovarian cancer. OCCC constitutes 25% of ovarian cancers in East Asia (Japan, Korea, China, Singapore) and 6–10% in Europe and North Amer...

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Detalles Bibliográficos
Autores principales: Chien, Wenwen, Tyner, Jeffrey W., Gery, Sigal, Zheng, Yueyuan, Li, Li-Yan, Gopinatha Pillai, Mohan Shankar, Nam, Chehyun, Bhowmick, Neil A., Lin, De-Chen, Koeffler, H. Phillip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122390/
https://www.ncbi.nlm.nih.gov/pubmed/37087441
http://dx.doi.org/10.1186/s13048-023-01160-y