Cullin 3–Mediated Regulation of Intracellular Iron Homeostasis Promotes Thymic Invariant NKT Cell Maturation

The E3 ubiquitin ligase cullin 3 (Cul3) is critical for invariant NKT (iNKT) cell development, as iNKT cells lacking Cul3 accumulate in the immature developmental stages. However, the mechanisms by which Cul3 mediates iNKT cell development remain unknown. In this study, we investigated the role of C...

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Detalles Bibliográficos
Autores principales: Yarosz, Emily L., Kumar, Ajay, Singer, Jeffrey D., Chang, Cheong-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2023
Materias:
Adaptive Immunity
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122431/
https://www.ncbi.nlm.nih.gov/pubmed/36951874
http://dx.doi.org/10.4049/immunohorizons.2300002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122431/
https://www.ncbi.nlm.nih.gov/pubmed/36951874
http://dx.doi.org/10.4049/immunohorizons.2300002

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