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Mitotic death: a mechanism of survival? A review

Mitotic death is a delayed response of p53 mutant tumours that are resistant to genotoxic damage. Questions surround why this response is so delayed and how its mechanisms serve a survival function. After uncoupling apoptosis from G1 and S phase arrests and adapting these checkpoints, p53 mutated tu...

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Detalles Bibliográficos
Autores principales: Erenpreisa, Jekaterina, Cragg, M S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC101225/
https://www.ncbi.nlm.nih.gov/pubmed/11983025
http://dx.doi.org/10.1186/1475-2867-1-1