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DNA-scaffolded multivalent vaccine against SARS-CoV-2

Short peptides are poor immunogens. One way to increase their immune responses is by arraying immunogens in multivalency. Simple and efficient scaffolds for spatial controlling the inter-antigen distance and enhancing immune activation are required. Here, we report a molecular vaccine design princip...

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Detalles Bibliográficos
Autores principales: Chen, Fangfang, Huang, Yuhan, Huang, Zhengyu, Jiang, Tingting, Yang, Zailin, Zeng, Jie, Jin, Aishun, Zuo, Hua, Huang, Cheng Zhi, Mao, Chengde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Acta Materialia Inc. Published by Elsevier Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122553/
https://www.ncbi.nlm.nih.gov/pubmed/37088158
http://dx.doi.org/10.1016/j.actbio.2023.04.017