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DNA-scaffolded multivalent vaccine against SARS-CoV-2

Short peptides are poor immunogens. One way to increase their immune responses is by arraying immunogens in multivalency. Simple and efficient scaffolds for spatial controlling the inter-antigen distance and enhancing immune activation are required. Here, we report a molecular vaccine design princip...

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Detalles Bibliográficos
Autores principales:	Chen, Fangfang, Huang, Yuhan, Huang, Zhengyu, Jiang, Tingting, Yang, Zailin, Zeng, Jie, Jin, Aishun, Zuo, Hua, Huang, Cheng Zhi, Mao, Chengde
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Acta Materialia Inc. Published by Elsevier Ltd. 2023
Materias:	Full Length Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122553/ https://www.ncbi.nlm.nih.gov/pubmed/37088158 http://dx.doi.org/10.1016/j.actbio.2023.04.017

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