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Self-replicating RNA nanoparticle vaccine elicits protective immune responses against SARS-CoV-2

The creation of safe and effective vaccines that induce potent cellular and humoral immune responses against SARS-CoV-2 is urgently needed to end the global COVID-19 epidemic. Here, we developed an alphavirus-derived self-replicating RNA (repRNA)-based vaccine platform encoding the receptor-binding...

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Detalles Bibliográficos
Autores principales: Lin, Guibin, Yan, Huan, Sun, Jing, Zhao, Jincun, Zhang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122567/
https://www.ncbi.nlm.nih.gov/pubmed/37151990
http://dx.doi.org/10.1016/j.omtn.2023.04.021