Caveolin-1-Mediated Cholesterol Accumulation Contributes to Exaggerated mGluR-Dependent Long-Term Depression and Impaired Cognition in Fmr1 Knockout Mice

Fragile X syndrome (FXS) is one of the most common inherited mental retardation diseases and is caused by the loss of fragile X mental retardation protein (FMRP) expression. The metabotropic glutamate receptor (mGluR) theory of FXS states that enhanced mGluR-dependent long-term depression (LTD) due...

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Detalles Bibliográficos
Autores principales: Luo, Li, Yang, Le, Zhang, Kun, Zhou, Shi-Meng, Wang, Yan, Yang, Liu-Kun, Feng, Bin, Liu, Shui-Bing, Wu, Yu-Mei, Zhao, Ming-Gao, Yang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122623/
https://www.ncbi.nlm.nih.gov/pubmed/36854997
http://dx.doi.org/10.1007/s12035-023-03269-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122623/
https://www.ncbi.nlm.nih.gov/pubmed/36854997
http://dx.doi.org/10.1007/s12035-023-03269-z

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