Cargando…

Caveolin-1-Mediated Cholesterol Accumulation Contributes to Exaggerated mGluR-Dependent Long-Term Depression and Impaired Cognition in Fmr1 Knockout Mice

Fragile X syndrome (FXS) is one of the most common inherited mental retardation diseases and is caused by the loss of fragile X mental retardation protein (FMRP) expression. The metabotropic glutamate receptor (mGluR) theory of FXS states that enhanced mGluR-dependent long-term depression (LTD) due...

Descripción completa

Detalles Bibliográficos
Autores principales:	Luo, Li, Yang, Le, Zhang, Kun, Zhou, Shi-Meng, Wang, Yan, Yang, Liu-Kun, Feng, Bin, Liu, Shui-Bing, Wu, Yu-Mei, Zhao, Ming-Gao, Yang, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122623/ https://www.ncbi.nlm.nih.gov/pubmed/36854997 http://dx.doi.org/10.1007/s12035-023-03269-z

Ejemplares similares

Longitudinal PET studies of mGluR5 in FXS using an FMR1 knockout mouse model
por: Afshar, Sepideh, et al.
Publicado: (2022)

Altered surface mGluR5 dynamics provoke synaptic NMDAR dysfunction and cognitive defects in Fmr1 knockout mice
por: Aloisi, Elisabetta, et al.
Publicado: (2017)

The effect of an mGluR5 inhibitor on procedural memory and avoidance discrimination impairments in Fmr1 KO mice
por: Veloz, M F Vinueza, et al.
Publicado: (2012)

The mGluR5 antagonist AFQ056 does not affect methylation and transcription of the mutant FMR1 gene in vitro
por: Tabolacci, Elisabetta, et al.
Publicado: (2012)

Analysis of the Gut Microbiota and Inflammatory Factors in mGluR5-Knockout Mice
por: Cai, Guohong, et al.
Publicado: (2020)

Imbalance between Glutamate and GABA in Fmr1 Knockout Astrocytes Influences Neuronal Development
por: Wang, Lu, et al.
Publicado: (2016)

Different Activity Patterns in Retinal Ganglion Cells of TRPM1 and mGluR6 Knockout Mice
por: Takeuchi, Haruki, et al.
Publicado: (2018)

mGluR5, CB1 and neuroprotection
por: Carvalho, Toniana G., et al.
Publicado: (2016)

The Changes in mGluR2 and mGluR7 Expression in Rat Medial Vestibular Nucleus and Flocculus Following Unilateral Labyrinthectomy
por: Zhou, Wen, et al.
Publicado: (2013)

Altered cortical Cytoarchitecture in the Fmr1 knockout mouse
por: Lee, Frankie H. F., et al.
Publicado: (2019)

Generation and Characterization of Fmr1 Knockout Zebrafish
por: den Broeder, Marjo J., et al.
Publicado: (2009)

The orthosteric agonist 2-chloro-5-hydroxyphenylglycine activates mGluR5 and mGluR1 with similar efficacy and potency
por: Kammermeier, Paul J
Publicado: (2012)

Comprehensive behavioral study of mGluR3 knockout mice: implication in schizophrenia related endophenotypes
por: Fujioka, Ryuta, et al.
Publicado: (2014)

Characterization of a mGluR5 Knockout Rat Model with Hallmarks of Fragile X Syndrome
por: Dahl, Victoria, et al.
Publicado: (2022)

Group I mGluRs in Therapy and Diagnosis of Parkinson’s Disease: Focus on mGluR5 Subtype
por: Azam, Shofiul, et al.
Publicado: (2022)

Gene expression analysis in Fmr1KO mice identifies an immunological signature in brain tissue and mGluR5-related signaling in primary neuronal cultures
por: Prilutsky, Daria, et al.
Publicado: (2015)

mGluR5 Is Substitutable for mGluR1 in Cerebellar Purkinje Cells for Motor Coordination, Developmental Synapse Elimination, and Motor Learning
por: Harbers, Maria, et al.
Publicado: (2022)

Metabotropic glutamate receptors (mGluRs) in epileptogenesis: an update on abnormal mGluRs signaling and its therapeutic implications
por: Huang, Leyi, et al.
Publicado: (2023)

Metabotropic glutamate receptor 1 (mGluR1) and 5 (mGluR5) regulate late phases of LTP and LTD in the hippocampal CA1 region in vitro
por: Neyman, Sergey, et al.
Publicado: (2008)

Opposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density
por: Gross, Kellie S., et al.
Publicado: (2016)

Loss of retinoid X receptor gamma subunit impairs group 1 mGluR mediated electrophysiological responses and group 1 mGluR dependent behaviors
por: Upreti, Chirag, et al.
Publicado: (2021)

Group I mGluR antagonist rescues the deficit of D1-induced LTP in a mouse model of fragile X syndrome
por: Xu, Zhao-Hui, et al.
Publicado: (2012)

Regulation of GABA Equilibrium Potential by mGluRs in Rat Hippocampal CA1 Neurons
por: Yang, Bo, et al.
Publicado: (2015)

Failed Stabilization for Long-Term Potentiation in the Auditory Cortex of Fmr1 Knockout Mice
por: Yang, Sungchil, et al.
Publicado: (2014)

Transgenerational deep sequencing revealed hypermethylation of hippocampal mGluR1 gene with altered mRNA expression of mGluR5 and mGluR3 associated with behavioral changes in Sprague Dawley rats with history of prolonged febrile seizure
por: Alese, Oluwole Ojo, et al.
Publicado: (2019)

Orchestrated activation of mGluR5 and CB(1) promotes neuroprotection
por: Batista, Edleusa M. L., et al.
Publicado: (2016)

Anti-mGluR1 encephalitis: Case illustration and systematic review
por: Khojah, Osama, et al.
Publicado: (2023)

Increased iron content in the heart of the Fmr1 knockout mouse
por: Talvio, Karo, et al.
Publicado: (2021)

Retinoic Acid Supplementation Rescues the Social Deficits in Fmr1 Knockout Mice
por: Yang, Liqin, et al.
Publicado: (2022)

Pretreatment with mGluR2 or mGluR3 Agonists Reduces Apoptosis Induced by Hypoxia-Ischemia in Neonatal Rat Brains
por: Bratek - Gerej, Ewelina, et al.
Publicado: (2021)

Transcription Repressor Hes1 Contributes to Neuropathic Pain Development by Modifying CDK9/RNAPII-Dependent Spinal mGluR5 Transcription
por: Hsieh, Ming-Chun, et al.
Publicado: (2019)

The thalamic mGluR1-PLCβ4 pathway is critical in sleep architecture
por: Hong, Joohyeon, et al.
Publicado: (2016)

Correction: Regulation of GABA Equilibrium Potential by mGluRs in Rat Hippocampal CA1 Neurons
por: Yang, Bo, et al.
Publicado: (2015)

Calpain-1 deletion impairs mGluR-dependent LTD and fear memory extinction
por: Zhu, Guoqi, et al.
Publicado: (2017)

Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism
por: Wang, Xiaoming, et al.
Publicado: (2016)

Investigating the role of mGluR2 versus mGluR3 in antipsychotic-like effects, sleep-wake architecture and network oscillatory activity using novel Han Wistar rats lacking mGluR2 expression
por: Wood, Christian M., et al.
Publicado: (2018)

Modeling mGluR1 mediated synaptic depression in cerebellar Purkinje cells
por: Su, Yizhen, et al.
Publicado: (2014)

Optogenetic activation of mGluR1 signaling in the cerebellum induces synaptic plasticity
por: Surdin, Tatjana, et al.
Publicado: (2022)

mGluR-Dependent Synaptic Plasticity in Drug-Seeking
por: Bellone, Camilla, et al.
Publicado: (2012)

PET imaging of mGluR5 in Alzheimer’s disease
por: Mecca, Adam P., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_b4mnl2su2n3lgh755g3qkn1ik5