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Chronic Cerebral Hypoperfusion-Induced Disturbed Proteostasis of Mitochondria and MAM Is Reflected in the CSF of Rats by Proteomic Analysis

Declining cerebral blood flow leads to chronic cerebral hypoperfusion which can induce neurodegenerative disorders, such as vascular dementia. The reduced energy supply of the brain impairs mitochondrial functions that could trigger further damaging cellular processes. We carried out stepwise bilate...

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Detalles Bibliográficos
Autores principales: Tukacs, Vanda, Mittli, Dániel, Hunyadi-Gulyás, Éva, Hlatky, Dávid, Medzihradszky, Katalin F., Darula, Zsuzsanna, Nyitrai, Gabriella, Czurkó, András, Juhász, Gábor, Kardos, József, Kékesi, Katalin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122630/
https://www.ncbi.nlm.nih.gov/pubmed/36808604
http://dx.doi.org/10.1007/s12035-023-03215-z