Siglec-6 mediates the uptake of extracellular vesicles through a noncanonical glycolipid binding pocket

Immunomodulatory Siglecs are controlled by their glycoprotein and glycolipid ligands. Siglec-glycolipid interactions are often studied outside the context of a lipid bilayer, missing the complex behaviors of glycolipids in a membrane. Through optimizing a liposomal formulation to dissect Siglec–glyc...

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Detalles Bibliográficos
Autores principales: Schmidt, Edward N., Lamprinaki, Dimitra, McCord, Kelli A., Joe, Maju, Sojitra, Mirat, Waldow, Ayk, Nguyen, Jasmine, Monyror, John, Kitova, Elena N., Mozaneh, Fahima, Guo, Xue Yan, Jung, Jaesoo, Enterina, Jhon R., Daskhan, Gour C., Han, Ling, Krysler, Amanda R., Cromwell, Christopher R., Hubbard, Basil P., West, Lori J., Kulka, Marianne, Sipione, Simonetta, Klassen, John S., Derda, Ratmir, Lowary, Todd L., Mahal, Lara K., Riddell, Meghan R., Macauley, Matthew S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122656/
https://www.ncbi.nlm.nih.gov/pubmed/37087495
http://dx.doi.org/10.1038/s41467-023-38030-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122656/
https://www.ncbi.nlm.nih.gov/pubmed/37087495
http://dx.doi.org/10.1038/s41467-023-38030-6

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