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GATA6 coordinates cross-talk between BMP10 and oxidative stress axis in pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a life-threatening condition characterized by a progressive increase in pulmonary vascular resistance leading to right ventricular failure and often death. Here we report that deficiency of transcription factor GATA6 is a shared pathological feature of PA end...

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Detalles Bibliográficos
Autores principales: Toyama, Tetsuo, Kudryashova, Tatiana V., Ichihara, Asako, Lenna, Stefania, Looney, Agnieszka, Shen, Yuanjun, Jiang, Lifeng, Teos, Leyla, Avolio, Theodore, Lin, Derek, Kaplan, Ulas, Marden, Grace, Dambal, Vrinda, Goncharov, Dmitry, Delisser, Horace, Lafyatis, Robert, Seta, Francesca, Goncharova, Elena A., Trojanowska, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122657/
https://www.ncbi.nlm.nih.gov/pubmed/37087509
http://dx.doi.org/10.1038/s41598-023-33779-8