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Network pharmacology identifies fisetin as a treatment for osteoporosis that activates the Wnt/β-catenin signaling pathway in BMSCs

BACKGROUND: Although fisetin may exist widely in many natural herbs, its anti-OP mechanism is still unclear. The aim of this study is to explore the molecular anti-osteoporosis (OP) mechanism of fisetin based on network pharmacology and cell experiments. METHODS: The target of fisetin was extracted...

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Detalles Bibliográficos
Autores principales: Liang, Guihong, Zhao, Jinlong, Pan, Jianke, Yang, Yuan, Dou, Yaoxing, Yang, Weiyi, Zeng, Lingfeng, Liu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122799/
https://www.ncbi.nlm.nih.gov/pubmed/37087476
http://dx.doi.org/10.1186/s13018-023-03761-1