Long term worsening of amyloid pathology, cerebral function, and cognition after a single inoculation of beta-amyloid seeds with Osaka mutation

ABSTRACT: Alzheimer’s disease (AD) is characterized by intracerebral deposition of abnormal proteinaceous assemblies made of amyloid-β (Aß) peptides or tau proteins. These peptides and proteins induce synaptic dysfunctions that are strongly correlated with cognitive decline. Intracerebral infusion o...

Descripción completa

Detalles Bibliográficos
Autores principales: Célestine, Marina, Jacquier-Sarlin, Muriel, Borel, Eve, Petit, Fanny, Perot, Jean-Baptiste, Hérard, Anne-Sophie, Bousset, Luc, Buisson, Alain, Dhenain, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122826/
https://www.ncbi.nlm.nih.gov/pubmed/37087498
http://dx.doi.org/10.1186/s40478-023-01559-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122826/
https://www.ncbi.nlm.nih.gov/pubmed/37087498
http://dx.doi.org/10.1186/s40478-023-01559-0

Ejemplares similares