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Thymidine Phosphorylase Deficiency or Inhibition Preserves Cardiac Function in Mice With Acute Myocardial Infarction

BACKGROUND: Ischemic cardiovascular disease is the leading cause of death worldwide. Current pharmacologic therapy has multiple limitations, and patients remain symptomatic despite maximal medical therapies. Deficiency or inhibition of thymidine phosphorylase (TYMP) in mice reduces thrombosis, sugge...

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Detalles Bibliográficos
Autores principales: Du, Lili, Yue, Hong, Rorabaugh, Boyd R., Li, Oliver Q. Y., DeHart, Autumn R., Toloza‐Alvarez, Gretel, Hong, Liang, Denvir, James, Thompson, Ellen, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122909/
https://www.ncbi.nlm.nih.gov/pubmed/36974758
http://dx.doi.org/10.1161/JAHA.122.028023