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Thymidine Phosphorylase Deficiency or Inhibition Preserves Cardiac Function in Mice With Acute Myocardial Infarction
BACKGROUND: Ischemic cardiovascular disease is the leading cause of death worldwide. Current pharmacologic therapy has multiple limitations, and patients remain symptomatic despite maximal medical therapies. Deficiency or inhibition of thymidine phosphorylase (TYMP) in mice reduces thrombosis, sugge...
Autores principales: | Du, Lili, Yue, Hong, Rorabaugh, Boyd R., Li, Oliver Q. Y., DeHart, Autumn R., Toloza‐Alvarez, Gretel, Hong, Liang, Denvir, James, Thompson, Ellen, Li, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122909/ https://www.ncbi.nlm.nih.gov/pubmed/36974758 http://dx.doi.org/10.1161/JAHA.122.028023 |
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