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Rac1 inhibition protects the kidney against kidney ischemia/reperfusion through the inhibition of macrophage migration
Kidney ischemia/reperfusion (I/R) injury, a common cause of acute kidney injury (AKI), is associated with the migration of inflammatory cells into the kidney. Ras-related C3 botulinum toxin substrate 1 (Rac1), a member of the Rho family of small GTPase, plays an important role in inflammatory cell m...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Physiological Society and The Korean Society of Pharmacology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122995/ https://www.ncbi.nlm.nih.gov/pubmed/37078299 http://dx.doi.org/10.4196/kjpp.2023.27.3.257 |