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Rac1 inhibition protects the kidney against kidney ischemia/reperfusion through the inhibition of macrophage migration

Kidney ischemia/reperfusion (I/R) injury, a common cause of acute kidney injury (AKI), is associated with the migration of inflammatory cells into the kidney. Ras-related C3 botulinum toxin substrate 1 (Rac1), a member of the Rho family of small GTPase, plays an important role in inflammatory cell m...

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Detalles Bibliográficos
Autores principales: Park, You Ri, Kong, Min Jung, Noh, Mi Ra, Park, Kwon Moo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122995/
https://www.ncbi.nlm.nih.gov/pubmed/37078299
http://dx.doi.org/10.4196/kjpp.2023.27.3.257