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Edaravone alleviates lung damage in mice with hypoxic pulmonary hypertension by increasing nitric oxide synthase 3 expression

This study is to determine the regulation of nitric oxide synthase 3 (NOS3) by edaravone in mice with hypoxic pulmonary hypertension (HPH). C57BL/6J mice were reared in a hypoxic chamber. HPH mice were treated with edaravone or edaravone + L-NMMA (a NOS inhibitor). Lung tissue was collected for hist...

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Detalles Bibliográficos
Autores principales: Zheng, Wan, Li, Tianfa, Wei, Junping, Yan, Yani, Yang, Shanshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122996/
https://www.ncbi.nlm.nih.gov/pubmed/37078295
http://dx.doi.org/10.4196/kjpp.2023.27.3.209