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Lyso-globotriaosylsphingosine induces endothelial dysfunction via autophagy-dependent regulation of necroptosis

Fabry disease is a lysosomal storage disorder characterized by the lysosomal accumulations of glycosphingolipids in a variety of cytotypes, which include endothelial cells. The disease is inherited and originates from an error in glycosphingolipid catabolism caused by insufficient α-galactosidase A...

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Detalles Bibliográficos
Autores principales: Hwang, Ae-Rang, Park, Seonghee, Woo, Chang-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122999/
https://www.ncbi.nlm.nih.gov/pubmed/37078297
http://dx.doi.org/10.4196/kjpp.2023.27.3.231