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Fitness functions for RNA structure design

An RNA design algorithm takes a target RNA structure and finds a sequence that folds into that structure. This is fundamentally important for engineering therapeutics using RNA. Computational RNA design algorithms are guided by fitness functions, but not much research has been done on the merits of...

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Detalles Bibliográficos
Autores principales: Ward, Max, Courtney, Eliot, Rivas, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123107/
https://www.ncbi.nlm.nih.gov/pubmed/36869673
http://dx.doi.org/10.1093/nar/gkad097