Cargando…

Homologous recombination suppresses transgenerational DNA end resection and chromosomal instability in fission yeast

Chromosomal instability (CIN) drives cell-to-cell heterogeneity, and the development of genetic diseases, including cancer. Impaired homologous recombination (HR) has been implicated as a major driver of CIN, however, the underlying mechanism remains unclear. Using a fission yeast model system, we e...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pai, Chen-Chun, Durley, Samuel C, Cheng, Wei-Chen, Chiang, Nien-Yi, Peters, Jennifer, Kasparek, Torben, Blaikley, Elizabeth, Wee, Boon-Yu, Walker, Carol, Kearsey, Stephen E, Buffa, Francesca, Murray, Johanne M, Humphrey, Timothy C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123110/ https://www.ncbi.nlm.nih.gov/pubmed/36951111 http://dx.doi.org/10.1093/nar/gkad160

Ejemplares similares

The DNA damage checkpoint pathway promotes extensive resection and nucleotide synthesis to facilitate homologous recombination repair and genome stability in fission yeast
por: Blaikley, Elizabeth J., et al.
Publicado: (2014)

The spliceosome-associated protein Nrl1 suppresses homologous recombination-dependent R-loop formation in fission yeast
por: Aronica, Lucia, et al.
Publicado: (2016)

Rapid regulation of protein activity in fission yeast
por: Bøe, Cathrine A, et al.
Publicado: (2008)

Homologous recombination repair intermediates promote efficient de novo telomere addition at DNA double-strand breaks
por: Davé, Anoushka, et al.
Publicado: (2020)

Monitoring DNA replication in fission yeast by incorporation of 5-ethynyl-2′-deoxyuridine
por: Hua, Hui, et al.
Publicado: (2011)

Genetic instability in budding and fission yeast—sources and mechanisms
por: Skoneczna, Adrianna, et al.
Publicado: (2015)

Microtubule nucleation and dynamic instability in interphase fission yeast
por: Liang, Xin
Publicado: (2019)

Expression of the cancer-associated DNA polymerase ε P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication
por: Soriano, Ignacio, et al.
Publicado: (2021)

Swi1(Timeless) Prevents Repeat Instability at Fission Yeast Telomeres
por: Gadaleta, Mariana C., et al.
Publicado: (2016)

Stress Activated Protein Kinase Pathway Modulates Homologous Recombination in Fission Yeast
por: Bellini, Angela, et al.
Publicado: (2012)

Homology-directed repair involves multiple strand invasion cycles in fission yeast
por: Vines, Amanda J., et al.
Publicado: (2022)

Multiple Regulation of Rad51-Mediated Homologous Recombination by Fission Yeast Fbh1
por: Tsutsui, Yasuhiro, et al.
Publicado: (2014)

Nuclear distribution and chromatin association of DNA polymerase α-primase is affected by TEV protease cleavage of Cdc23 (Mcm10) in fission yeast
por: Yang, Xiaowen, et al.
Publicado: (2005)

The Fission Yeast XMAP215 Homolog Dis1p Is Involved in Microtubule Bundle Organization
por: Roque, Hélio, et al.
Publicado: (2010)

Short-Homology-Mediated CRISPR/Cas9-Based Method for Genome Editing in Fission Yeast
por: Hayashi, Aki, et al.
Publicado: (2019)

The fission yeast FHIT homolog affects checkpoint control of proliferation and is regulated by mitochondrial electron transport
por: Sjölander, Johanna J., et al.
Publicado: (2019)

Fission yeast septation
por: Cortés, Juan C. G., et al.
Publicado: (2016)

Fission yeast CK1 promotes DNA double-strand break repair through both homologous recombination and non-homologous end joining
por: Cullati, Sierra N., et al.
Publicado: (2023)

Co-transcriptional RNA cleavage by Drosha homolog Pac1 triggers transcription termination in fission yeast
por: Yague-Sanz, Carlo, et al.
Publicado: (2021)

Geometric instability catalyzes mitochondrial fission
por: Irajizad, Ehsan, et al.
Publicado: (2019)

Nuclear Mechanics in the Fission Yeast
por: Gallardo, Paola, et al.
Publicado: (2019)

Fission Yeast Autophagy Machinery
por: Xu, Dan-Dan, et al.
Publicado: (2022)

Vgl1, a multi-KH domain protein, is a novel component of the fission yeast stress granules required for cell survival under thermal stress
por: Wen, Wei-Ling, et al.
Publicado: (2010)

Inhibition of peroxisome fission, but not mitochondrial fission, increases yeast chronological lifespan
por: Lefevre, Sophie D, et al.
Publicado: (2015)

Nuclear size control in fission yeast
por: Neumann, Frank R., et al.
Publicado: (2007)

FYPO: the fission yeast phenotype ontology
por: Harris, Midori A., et al.
Publicado: (2013)

Fitness Landscape of the Fission Yeast Genome
por: Grech, Leanne, et al.
Publicado: (2019)

Forces that shape fission yeast cells
por: Chang, Fred
Publicado: (2017)

Optimization of a microarray for fission yeast
por: Kim, Dong-Uk, et al.
Publicado: (2019)

Subtelomeric Chromatin in the Fission Yeast S. pombe
por: Yadav, Rajesh K., et al.
Publicado: (2021)

The fission yeast pleckstrin homology domain protein Spo7 is essential for initiation of forespore membrane assembly and spore morphogenesis
por: Nakamura-Kubo, Michiko, et al.
Publicado: (2011)

Identification and Functional Analysis of the erh1 (+) Gene Encoding Enhancer of Rudimentary Homolog from the Fission Yeast Schizosaccharomyces pombe
por: Krzyzanowski, Marek K., et al.
Publicado: (2012)

Genomic Instability and Cellular Senescence: Lessons From the Budding Yeast
por: Lee, Jee Whu, et al.
Publicado: (2021)

The Global Transcriptional Response of Fission Yeast to Hydrogen Sulfide
por: Jia, Xu, et al.
Publicado: (2011)

Tertiary Epimutations – A Novel Aspect of Epigenetic Transgenerational Inheritance Promoting Genome Instability
por: McCarrey, John R., et al.
Publicado: (2016)

A family of C. elegans VASA homologs control Argonaute pathway specificity and promote transgenerational silencing
por: Dai, Siyuan, et al.
Publicado: (2022)

A Centromere DNA-binding Protein from Fission Yeast Affects Chromosome Segregation and Has Homology to Human CENP-B
por: Halverson, Dana, et al.
Publicado: (1997)

The CDK-Activating Kinase (CAK) Csk1 Is Required for Normal Levels of Homologous Recombination and Resistance to DNA Damage in Fission Yeast
por: Gerber, Hilary B., et al.
Publicado: (2008)

Mdb1, a Fission Yeast Homolog of Human MDC1, Modulates DNA Damage Response and Mitotic Spindle Function
por: Wei, Yi, et al.
Publicado: (2014)

Fission Yeast Hotspot Sequence Motifs Are Also Active in Budding Yeast
por: Steiner, Walter W., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_c5qpbeija41ss6pegtm6a5spkh