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Tissue-specific regulation of gene expression via unproductive splicing

Eukaryotic gene expression is regulated post-transcriptionally by a mechanism called unproductive splicing, in which mRNA is triggered to degrade by the nonsense-mediated decay (NMD) pathway as a result of regulated alternative splicing (AS). Only a few dozen unproductive splicing events (USEs) are...

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Detalles Bibliográficos
Autores principales: Mironov, Alexei, Petrova, Marina, Margasyuk, Sergey, Vlasenok, Maria, Mironov, Andrey A, Skvortsov, Dmitry, Pervouchine, Dmitri D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123112/
https://www.ncbi.nlm.nih.gov/pubmed/36912101
http://dx.doi.org/10.1093/nar/gkad161