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Unusual enantioselective cytoplasm-to-nucleus translocation and photosensitization of the chiral Ru(II) cationic complex via simple ion-pairing with lipophilic weak acid counter-anions

Targeted and enantioselective delivery of chiral diagnostic-probes and therapeutics into specific compartments inside cells is of utmost importance in the improvement of disease detection and treatment. The classical DNA ‘light-switch’ ruthenium(II)-polypyridyl complex, [Ru(DIP)(2)(dppz)]Cl(2) (DIP ...

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Detalles Bibliográficos
Autores principales: Chao, Xi-Juan, Huang, Chun-Hua, Tang, Miao, Yan, Zhu-Ying, Huang, Rong, Li, Yan, Zhu, Ben-Zhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123113/
https://www.ncbi.nlm.nih.gov/pubmed/36938880
http://dx.doi.org/10.1093/nar/gkad155