Systematic identification of factors involved in the silencing of germline genes in mouse embryonic stem cells

In mammals, many germline genes are epigenetically repressed to prevent their illegitimate expression in somatic cells. To advance our understanding of the mechanisms restricting the expression of germline genes, we analyzed their chromatin signature and performed a CRISPR-Cas9 knock-out screen for...

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Detalles Bibliográficos
Autores principales: Al Adhami, Hala, Vallet, Judith, Schaal, Celia, Schumacher, Paul, Bardet, Anaïs Flore, Dumas, Michael, Chicher, Johana, Hammann, Philippe, Daujat, Sylvain, Weber, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123117/
https://www.ncbi.nlm.nih.gov/pubmed/36772830
http://dx.doi.org/10.1093/nar/gkad071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123117/
https://www.ncbi.nlm.nih.gov/pubmed/36772830
http://dx.doi.org/10.1093/nar/gkad071

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