Insights into translocation mechanism and ribosome evolution from cryo-EM structures of translocation intermediates of Giardia intestinalis

Giardia intestinalis is a protozoan parasite that causes diarrhea in humans. Using single-particle cryo-electron microscopy, we have determined high-resolution structures of six naturally populated translocation intermediates, from ribosomes isolated directly from actively growing Giardia cells. The...

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Detalles Bibliográficos
Autores principales: Majumdar, Soneya, Emmerich, Andrew, Krakovka, Sascha, Mandava, Chandra Sekhar, Svärd, Staffan G, Sanyal, Suparna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123126/
https://www.ncbi.nlm.nih.gov/pubmed/36912103
http://dx.doi.org/10.1093/nar/gkad176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123126/
https://www.ncbi.nlm.nih.gov/pubmed/36912103
http://dx.doi.org/10.1093/nar/gkad176

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