Predicting individual-specific cardiotoxicity responses induced by tyrosine kinase inhibitors

Introduction: Tyrosine kinase inhibitor drugs (TKIs) are highly effective cancer drugs, yet many TKIs are associated with various forms of cardiotoxicity. The mechanisms underlying these drug-induced adverse events remain poorly understood. We studied mechanisms of TKI-induced cardiotoxicity by inte...

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Detalles Bibliográficos
Autores principales: Shim, Jaehee V., Xiong, Yuguang, Dhanan, Priyanka, Dariolli, Rafael, Azeloglu, Evren U., Hu, Bin, Jayaraman, Gomathi, Schaniel, Christoph, Birtwistle, Marc R., Iyengar, Ravi, Dubois, Nicole C., Sobie, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123273/
https://www.ncbi.nlm.nih.gov/pubmed/37101545
http://dx.doi.org/10.3389/fphar.2023.1158222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123273/
https://www.ncbi.nlm.nih.gov/pubmed/37101545
http://dx.doi.org/10.3389/fphar.2023.1158222

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