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Genetic variants in genes involved in creatine biosynthesis in patients with severe obesity or anorexia nervosa

Increased thermogenesis in brown adipose tissue might have an obesity-reducing effect in humans. In transgenic mice, depletion of genes involved in creatine metabolism results in disrupted thermogenic capacity and altered effects of high-fat feeding on body weight. Data analyses of a sex-stratified...

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Detalles Bibliográficos
Autores principales: Rajcsanyi, Luisa S., Hoffmann, Anne, Ghosh, Adhideb, Matrisch-Dinkler, Birgit, Zheng, Yiran, Peters, Triinu, Sun, Wenfei, Dong, Hua, Noé, Falko, Wolfrum, Christian, Herpertz-Dahlmann, Beate, Seitz, Jochen, de Zwaan, Martina, Herzog, Wolfgang, Ehrlich, Stefan, Zipfel, Stephan, Giel, Katrin, Egberts, Karin, Burghardt, Roland, Föcker, Manuel, Tsai, Linus T., Müller, Timo D., Blüher, Matthias, Hebebrand, Johannes, Hirtz, Raphael, Hinney, Anke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123275/
https://www.ncbi.nlm.nih.gov/pubmed/37101650
http://dx.doi.org/10.3389/fgene.2023.1128133