The human P2X7 receptor alters microglial morphology and cytokine secretion following immunomodulation

Introduction: In recent years, purinergic signaling via the P2X7 receptor (P2X7R) on microglia has repeatedly been implicated in depression genesis. However, it remains unclear which role the human P2X7R (hP2X7R) plays in regulating both microglia morphology and cytokine secretion upon different env...

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Detalles Bibliográficos
Autores principales: von Mücke-Heim, Iven-Alex, Martin, Jana, Uhr, Manfred, Ries, Clemens, Deussing, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123291/
https://www.ncbi.nlm.nih.gov/pubmed/37101546
http://dx.doi.org/10.3389/fphar.2023.1148190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123291/
https://www.ncbi.nlm.nih.gov/pubmed/37101546
http://dx.doi.org/10.3389/fphar.2023.1148190

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