DEEPCYPs: A deep learning platform for enhanced cytochrome P450 activity prediction

Cytochrome P450 (CYP) is a superfamily of heme-containing oxidizing enzymes involved in the metabolism of a wide range of medicines, xenobiotics, and endogenous compounds. Five of the CYPs (1A2, 2C9, 2C19, 2D6, and 3A4) are responsible for metabolizing the vast majority of approved drugs. Adverse dr...

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Detalles Bibliográficos
Autores principales: Ai, Daiqiao, Cai, Hanxuan, Wei, Jiajia, Zhao, Duancheng, Chen, Yihao, Wang, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123292/
https://www.ncbi.nlm.nih.gov/pubmed/37101544
http://dx.doi.org/10.3389/fphar.2023.1099093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123292/
https://www.ncbi.nlm.nih.gov/pubmed/37101544
http://dx.doi.org/10.3389/fphar.2023.1099093

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