Intravitreal Administration of AAV2-SIRT1 Reverses Diabetic Retinopathy in a Mouse Model of Type 2 Diabetes

PURPOSE: The expression of silent information regulator (SIRT) 1 is reduced in diabetic retinopathy (DR). Previous studies showed that alterations in SIRT1 messenger RNA (mRNA) and protein expression are implicated in progressive inflammation and formation of retinal acellular capillaries. Treatment...

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Detalles Bibliográficos
Autores principales: Adu-Agyeiwaah, Yvonne, Vieira, Cristiano P., Asare-Bediako, Bright, Li Calzi, Sergio, DuPont, Mariana, Floyd, Jason, Boye, Sanford, Chiodo, Vince, Busik, Julia V., Grant, Maria B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123324/
https://www.ncbi.nlm.nih.gov/pubmed/37070938
http://dx.doi.org/10.1167/tvst.12.4.20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10123324/
https://www.ncbi.nlm.nih.gov/pubmed/37070938
http://dx.doi.org/10.1167/tvst.12.4.20

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